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BNP Letrozole(Femara)For Bodybuilding CAS:112809-51-5

BNP Letrozole(Femara)For Bodybuilding CAS:112809-51-5

Letrozole (popular name Femara among others) is a non suicidal Aromatase Inhibitor (AI) that comes as an oral pill. According to both studies and people who experimented with it – this is the most potent Aromatase Inhibitor out there. Letrozole is one of the three most popular and commonly used AIs by steroid users for controlling the side effects associated with high estrogen levels as a result of using aromatizing steroids. Those steroids that convert into estrogen through the process of aromatization (binding to aromatase enzymes). Letrozole is binding to those aromatase enzymes not allowing steroids to do so, thus, lowering estrogen. Therefore, it protects from high estrogenic symptoms and steroids side effects. But since Letrozole is so powerful at reducing estrogen levels, it’s often seen as a last resort drug. That’s why it is perhaps the least popular out of the three AIs. Being so powerful, users are likely to suppress estrogen levels too much. Therefore, they only keep it as a drug that is going to be helpful in lowering estrogen in case the other two fail. Generally, I have to mention that there’s literally nothing else better that could help you deal with gynecomastia. Letrozole is the best anti-gynecomastia drug in existence. But it is also helpful in lowering the risks of other high estrogen symptoms too. Such as water retention, high blood pressure, and others.

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Description

    What is Letrozole (Femara)?
    Letrozolexin Letrozole Euro-PharmaciesExactly like all other Aromatase Inhibitors that people use for protection against the high estrogenic side effects of anabolic steroids, Letrozole is a drug that was developed and is still approved by the FDA for treating hormonally positive breast cancer in women.

    This is a drug that lowers estrogen. And in case the cancer is caused by estrogen, Letrozole can be highly effective for treating breast cancer in women. But there are other uses as well when the patient may need to lower estrogen levels.

    But the most important thing that you should be aware of is that Letrozole (Femara) is able to lower the overall estrogen levels as a result of blocking aromatase enzymes. And it has the most powerful estrogen reducing effects.

    Although SERMs are also anti-estrogens, they are very different from Aromatase Inhibitors (AIs). They don't lower estrogen levels, they block the estrogen receptors in specific parts of the body.
    That's why Letrozole is helpful at mitigating water retention, high blood pressure that comes along with the excess of water retention, and other high estrogen symptoms. Nonetheless, the most popular use of Letrozole is to deal with gynecomastia (man's boobs).

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Letrozole-in-Bodybuilding

let's go through some uses of the drug in males:

    To treat infertility – high estrogen levels may be linked to rapid weight gain which may eventually lead to obesity. Obesity stimulates estrogen production which in turn leads to weight gain. Obesity can lead to infertility due to low testosterone levels and low sperm count. The aromatase enzyme is prevalent in fat and converts androgens like testosterone into estrogen. If the drug is taken in low doses, aromatase enzyme is inhibited as the drug binds to the enzyme, estrogen levels decrease, testosterone levels are normalized and sperm count is increased.
    To treat gynecomastia – it is a condition in which males have enlarged breasts, it mainly affects men who are bodybuilders during anabolic steroid use, although a man may experience it in other instances, for example during hormonal therapy to treat prostate cancer. The dosage of Letrozole is determined by the amount of anabolic steroid one is using. However, it also depends on the response of the first dose and the side effects; to detect the presence of the negative effects, blood tests are carried out. The aromatase inhibitor works very fast to reverse the side effects of steroids use, thus it can be used in emergency situations.
    When estrogen levels are reduced as the actions of the enzyme are blocked, the symptoms of high estrogen outlined at the begging of the article improve. The good thing with the drug is that it is not a suicidal AI, meaning its wanted effects aren't permanent; it does not disable the aromatase enzyme permanently. However, it's more powerful at reducing estrogen levels when compared to Arimidex or Aromasin. The drug shouldn't be abused, without the supervision of a doctor.

Letrozole Side Effects

    So, you know that Letrozole is doing a great job in protecting and controlling (lowering) high estrogen symptoms. This is a drug that you should have handy in case you're thinking of introducing anabolic steroids to your regimen (those that aromatize into estrogen). That's because this way you can use it whenever you notice high estrogen symptoms and get the protection.

    Nonetheless, never underestimate Letrozole side effects. By administering too high a Letrozole dosage, this drug is going to reduce too much estrogen levels. While you may think that estrogen is a female hormone so there's no need for it – you're making a huge mistake.

Letrozole Dosage

    Femara (Letrozole) is very powerful so you need to be very careful with it. It comes in the form of oral pills. I recommend using low doses because it's likely to cause powerful estrogen reduction effects even at low doses.

    I recommend using one dosage and waiting a few days and checking the results you're experiencing before taking another one. Do not attempt to use it too often. Some people may need to use it only once a week, others may find the need to use it even less frequently. Yes, there are cases when some people may need to use it on a daily or every other day basis, but obviously, this increases the risk of suppressing estrogen levels too much.

    It's very important to maintain a sensible dose. Find what's your best dosage because it varies from one person to another depending on a lot of factors such as steroids dosage, steroids number, cycle length, your personal response, and liability to convert into estrogen, and so on and so forth.

    Dosages of about 0.5-1.25 mg every two days are enough to offer perfect estrogenic protection for most men. Only in case you notice some signs of gynecomastia, you could up the dosage to 2.5 mg every other day or even daily but that's very rarely needed.

Natural Aromatase Inhibitors for Men

    Some men may not tolerate the side effects of the drug. Since the effects of the drug aren't permanent, you may also try using some natural aromatase inhibitors such as:

    1.Zinc – it's a proven a powerful natural estrogen blocker that inhibits the aromatase enzyme. The mineral not only decreases estrogen levels, but it also increases testosterone, hence boosting sperm count.

    2.Celery – it triggers the production of androsterone which stimulates an increase of testosterone hormone. Additionally, it contains a flavonoid known as apigenin that is believed to have a strong aromatase inhibiting effect. Celery can be taken in the form of juice or with fruits like apples or take it as you desire.

    3.Resveratrol – it's a chemical compound produced by plants when attacked by bacteria or fungi. Large concentrations are found in grapes but in the skin. Red wine contains resveratrol and one can drink it but in moderation. Other sources are peanut, berries, cocoa, and blueberries.

    4.White mushrooms – they boost testosterone hormone thus sperm count is also increased. They can also be beneficial to women with breast cancer due to their effects of estrogen reduction.

    5.Cruciferous vegetables – eat cruciferous vegetables daily to increase testosterone and lower estrogen naturally. They are rich in phytochemicals that block estrogen in the body. These vegetables contain DIM (diindolylmethane) which promotes estrogen metabolism, and then it's eliminated through the liver. Rich sources are broccoli, cauliflower, cabbage, Brussels sprouts, and kales.

    6.Seeds – some seeds like sesame and pomegranate seeds have a high quantity of polyphenols, which reduce estrogen in the bloodstream.

Conclusion

    Letrozole is the most powerful aromatase inhibitor so you need to be very careful with it. You need to use it to control estrogen. The point of using Letrozole (Femara) is to keep estrogen within the normal range. Getting estrogen too low or too high is causing side effects. So, you have to find your perfect Letrozole dosage specifically for you and your needs.

Clinical Data

Brand

BNP

Trade names

Femara,letrozole

CAS

112809-51-5

Molar mass

285.310

MF

C17H11N5

Purity

Above 98%

Apprarance

2.5mg*100

 

 

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Letrozole Dosage for Increased Endogenous Testosterone Secretion and PCT

    This AI may have some ability to raise testosterone levels, mainly through its ability to reduce estrogen. Both luteinizing hormone and follicle-stimulating hormone have been shown to be able to be increased by Letrozole, and these are essential to the production of testosterone.

    So while a reduction of estrogen is important for bringing about a rise in testosterone levels, this is a fine balance in men, and reducing estrogen too low can actually have the opposite effect, with testosterone not able to increase to a normal level if estrogen is suppressed too powerfully, which Letrozole has the ability to do.

    For this reason many will choose not to make use of this drug during post-cycle therapy at all in favor of using a SERM like Nolvadex. However, suppose you find that Letrozole is preferable for you for post-cycle therapy use. In that case, a low dose similar to or lower than that stated above during your steroid cycle is the only way to reduce the risk of very low estrogen occurring.

    Making use of Letrozole alongside Nolvadex, which is a staple in PCT for most men, results in both drugs, making the other less effective. Combining these drugs is not recommended for PCT. Therefore, most people will opt to use the better PCT option in the SERM Nolvadex while enjoying the benefits that Letrozole can provide during the steroid cycle only.

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