Letrozole (femara) is the strongest oral aromatase inhibitor (AI) available, and studies have shown that it will drop estrogen levels in men by 65% and 98% in women. Hence, this makes letro more powerful than the popular AI's aromasin and arimidex (anastrozole). Part of the reason it is so strong is because it acts on competitive/reversible binding to the protein enzyme.
Therefore, if a person finds themselves in trouble with high estrogen levels, letrozole can be used in a pinch to quickly halt gyno in its tracks before it gets worse.
https://www.hormonerawsource.com/steroid-finished/steroid-finished-tablets/premium-brand-stromusc-letrozole-femara-2-5mg.html
