
HEPIUS Finasteride CAS:98319-26-7
Finasteride is a synthetic 4-azasteroid compound known for its ability to inhibit the action of the enzyme 5-alpha-reductase. This enzyme is crucial in the conversion of testosterone into dihydrotestosterone (DHT), a hormone associated with conditions like androgenic alopecia (male pattern baldness) and benign prostatic hyperplasia (BPH). Finasteride is widely prescribed to manage these conditions by reducing DHT levels in the body.
Introduction to Finasteride
Finasteride is a synthetic 4-azasteroid compound known for its ability to inhibit the action of the enzyme 5-alpha-reductase. This enzyme is crucial in the conversion of testosterone into dihydrotestosterone (DHT), a hormone associated with conditions like androgenic alopecia (male pattern baldness) and benign prostatic hyperplasia (BPH). Finasteride is widely prescribed to manage these conditions by reducing DHT levels in the body.

Chemical Structure and Properties
Finasteride's chemical formula is C23H36N2O2, and its molecular weight is 372.54 g/mol. It is a white crystalline powder, practically insoluble in water but freely soluble in alcohol and other organic solvents. Finasteride is classified as a selective inhibitor of Type II 5-alpha-reductase, differentiating it from broader-spectrum inhibitors.
Applications of Finasteride
1.Androgenic Alopecia (Hair Loss Treatment):
●Finasteride is commonly marketed under the brand name Propecia for the treatment of male pattern baldness. By reducing DHT levels in the scalp, it slows hair loss and may promote hair regrowth in some individuals.
2.Benign Prostatic Hyperplasia (BPH):
●Finasteride is also sold under the brand name Proscar for the treatment of BPH. It works by shrinking the prostate, reducing urinary retention symptoms such as difficulty urinating, weak urine flow, and frequent urges to urinate, especially at night.
3.Hormonal Management:
●Finasteride has been explored in treating conditions related to excessive androgen activity, such as hirsutism in women and hormone therapy in transgender individuals.
Benefits of Finasteride
●Effective Hair Loss Prevention: Finasteride has demonstrated significant success in halting hair loss and stimulating regrowth in many patients.
●Prostate Health Improvement: It effectively reduces prostate volume in individuals suffering from BPH, improving urinary flow and reducing discomfort.
●Hormone Regulation: By lowering DHT levels, Finasteride helps maintain hormonal balance in androgen-sensitive tissues.
●Minimal Side Effects (in recommended doses): Finasteride is generally well-tolerated when taken under medical supervision.
Dosage and Administration
●For Hair Loss (Androgenic Alopecia): The standard dosage is 1 mg per day. This is typically administered orally with or without food. Consistency in timing ensures stable blood levels.
●For BPH Treatment: The recommended dosage is 5 mg per day. This dosage is also taken orally.
●For Experimental or Hormonal Uses: Dosages may vary based on individual conditions, but medical consultation is essential to tailor treatment.
Finasteride Cycle and Duration
●For Hair Loss Treatment: Results may begin to appear after 3 to 6 months of consistent use. Full benefits are often observed after 12 months. Continuous use is necessary to maintain results; discontinuing the drug may lead to a return of hair loss within a year.
●For BPH: Improvements in prostate health are usually noticeable after 3 to 6 months of daily use. Long-term treatment may be recommended to sustain benefits.
Half-Life of Finasteride
Finasteride has an elimination half-life of approximately 4 to 6 hours in younger individuals and 8 hours in older adults. This relatively short half-life necessitates daily administration to maintain stable blood concentrations. Despite the short half-life, DHT suppression effects can persist for up to 7 days post-administration.
Post-Cycle Therapy (PCT)
While Finasteride does not directly suppress testosterone production like anabolic steroids, post-cycle therapy (PCT) may still be necessary in specific scenarios:
●Hormonal Imbalance Restoration: Finasteride's DHT reduction may lead to altered hormonal profiles. A balanced PCT with natural testosterone boosters may help restore optimal androgen levels.
●Supplements for Hair Health: Biotin, zinc, and saw palmetto are commonly recommended during PCT to promote hair regrowth and minimize shedding.
Potential Side Effects
Although Finasteride is generally well-tolerated, some side effects may occur:
●Sexual Dysfunction: Decreased libido, erectile dysfunction, and reduced semen volume may occur but are often reversible upon discontinuation.
●Mood Changes: Depression, anxiety, or mood swings have been reported in rare cases.
●Gynecomastia (Male Breast Enlargement): Hormonal shifts may contribute to this condition, requiring medical attention.
●Allergic Reactions: Rash, itching, or swelling are rare but possible side effects requiring immediate medical care.
Precautions and Contraindications
●Pregnancy Warning: Finasteride can cause severe birth defects if handled by or ingested by pregnant women. Precautions should be taken to prevent exposure.
●Pre-existing Conditions: Individuals with liver disease should consult a healthcare provider before use, as Finasteride is metabolized in the liver.
●Drug Interactions: Finasteride may interact with certain medications; consult a physician for compatibility guidance.
Clinical Data
| Brand |
HEPIUS |
|
Trade names |
Proscar, Propecia, Damocare, Finpecia, Finide, Fincar, Finax, Pronor,Finasteride |
|
CAS |
98319-26-7 |
|
Molar mass |
372.549 |
|
Formula |
C23H36N2O2 |
|
Purity |
Above 98% |
|
Apprarance |
5mg*100 |
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Conclusion
Finasteride is a powerful and widely used medication for managing hair loss, BPH, and hormonal imbalances. Its targeted action in reducing DHT levels makes it effective with minimal side effects when used correctly. By adhering to proper dosage, cycle management, and monitoring for side effects, Finasteride can provide significant therapeutic benefits. However, professional medical supervision is essential to ensure safe and optimal outcomes.
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