The CAS number 139755-83-2 is the unique numerical identifier assigned by the Chemical Abstracts Service to sildenafil citrate, the active ingredient in Viagra. A CAS (Chemical Abstracts Service) number is a unique identifier for chemical substances, including compounds, polymers, biological sequences, mixtures, and alloys. Each CAS number is specific to only one substance, making it a reliable way to identify and access detailed information about a chemical.
Sildenafil citrate, identified by CAS 139755-83-2, is a white to off-white crystalline powder with a molecular formula of C22H30N6O4S and a molecular weight of 474.58 g/mol. It is highly soluble in water and slightly soluble in ethanol. This compound functions as a selective inhibitor of the enzyme phosphodiesterase type 5 (PDE5), which is predominantly found in the smooth muscle of the corpus cavernosum in the penis, as well as in the retina.
The CAS number is particularly useful for researchers, pharmacists, and regulatory agencies as it allows them to precisely identify sildenafil citrate in scientific literature, product formulations, and regulatory documents. This specificity is crucial in the pharmaceutical industry, where the exact identification of compounds can impact drug development, quality control, and regulatory compliance.
Sildenafil citrate's therapeutic application is primarily in the treatment of erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). In ED, sildenafil citrate helps to enhance erectile response when a man is sexually stimulated. In PAH, it helps to relax the blood vessels in the lungs, allowing blood to flow more easily.
The use of CAS numbers, like 139755-83-2, simplifies the global exchange of chemical information and supports the safe and effective use of chemical substances. It ensures that professionals across various fields can unequivocally identify substances and access detailed chemical and regulatory information, which is vital for research, clinical use, and safety compliance.
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